Member Publications

Peer-reviewed research from the CANDY Lab

All Publications Open Access / Free to Read

2026

Childhood Maltreatment and Deviations from Normative Brain Structure: A Mega-Analysis of 3,711 Individuals from the ENIGMA MDD and ENIGMA PTSD Working Groups

Wang HR, ENIGMA MDD Working Group, ENIGMA PTSD Working Group, Ho TC. Biological Psychiatry

2025

Value-Based Cognitive Control Moderates the Relation of Inflammation with Depression in Adolescents FREE TO READ

Yuan JP, Miller JG, Joachimsthaler J, Uy JP, Ho TC, Gotlib IH. Social Cognitive and Affective Neuroscience  Read it free ↗

Editorial: The exposome and the developing brain: understanding mechanisms of neuroplasticity

Ho TC. Neuropsychopharmacology

Interleukin-6 and Tumor Necrosis Factor-Alpha as Predictive Biomarkers for Depression and Mania in Young Adults with Mood Disorders FREE TO READ

S Liu, G Morgan-Fleming, DM Denenny, SJ Frey, MR Irwin, DJ Miklowitz, Ho TC. Journal of Psychiatric Research  Read it free ↗

Connectome-based predictive models optimized for sleep differentiate patients with depression from psychiatrically healthy controls FREE TO READ

Mummaneni A, Amir C, Allen NB, Ho TC. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging  Read it free ↗

Inflexible functional connectivity from rest to acute stress in alcohol use disorder FREE TO READ

Kirsch DE, Ho TC, Wassum KM, Ray LA, Grodin EN. Addiction Biology  Read it free ↗

The effects of the COVID-19 pandemic on neurobiological functioning in adolescents FREE TO READ

Yuan JP, Borchers LB, Lee Y, Buthmann J, Coury SM, Joachimsthaler J, Jaeger E, Ho TC, Gotlib IH. Translational Psychiatry  Read it free ↗

Peripheral microRNA signatures in adolescent depression FREE TO READ

Morgunova A, O’Toole N, Abboud F, Coury SM, Chen GG, Teixeira M, Turecki G, Silveira PP, Gifuni AJ, Gotlib IH, Nagy C, Meaney MJ, Ho TC, Flores C. Biological Psychiatry: Global Open Science  Read it free ↗

2024

A mega-analysis of functional connectivity and network abnormalities in youth depression FREE TO READ

Tse NY, Ratheesh A, Tian YE, Connolly CG, Davey CG, Ganesan S, Gotlib IH, Harrison BJ, Han LKM, Ho TC, Jamieson AJ, Kirshenbaum JS, Liu Y, Ma X, Ojha A, Qiu J, Sacchet MD, Schmaal L, Simmons AN, Suckling J, Wei D, Yang X, Yang TT, Cash RFH, Zalesky A. Nature Mental Health  Read it free ↗

Socioeconomic disadvantage moderates the association of systemic inflammation with amygdala volume in adolescents over a 2-year interval: an exploratory study FREE TO READ

Yuan JP, Jaeger EL, Coury SM, Uy JP, Buthmann JL, Ho TC, Gotlib IH. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging  Read it free ↗

Neural correlates of depression-related smartphone language use in adolescents FREE TO READ

McNeilly EA, Teresi GI, Coury SM, Bajwa Z, Kahn LE, Crowley R, Allen NB, Ho TC. NPP – Digital Psychiatry and Neuroscience  Read it free ↗

Threat- and reward-related brain circuitry, perceived stress, and anxiety in adolescents during the COVID-19 pandemic: a longitudinal investigation FREE TO READ

Borchers LR, Gifuni AJ, Ho TC, Kirshenbaum JS, Gotlib IH. Social Cognitive and Affective Neuroscience  Read it free ↗

Examining putamen resting-state connectivity markers of suicide attempt history in depressed adolescents FREE TO READ

Tymofiyeva O, Ho TC, Connolly CG, Gorrell S, Rampersaud R, Darrow SM, Max JE, Yang TT. Frontiers in Psychiatry  Read it free ↗

Neighborhood disadvantage and parenting predict longitudinal clustering of uncinate fasciculus microstructural integrity and clinical symptomatology in adolescents FREE TO READ

Buthmann JL, Uy JP, Yuan JP, Coury SM, Ho TC, Gotlib IH. Developmental Cognitive Neuroscience  Read it free ↗

Exploring sex differences in trajectories of pubertal development and mental health following early adversity FREE TO READ

Ho TC, Buthmann JL, Chahal R, Miller JG, Gotlib IH. Psychoneuroendocrinology  Read it free ↗

Protocol for teen inflammation glutamate emotion research (TIGER): Toward predictors of treatment response and clinical course in depressed adolescents FREE TO READ

Coury SM, López V, Bajwa Z, Garcia JM, Teresi GI, Kuhlman KR, Li Y, Cole S, Miklowitz DJ, Pappas I, Ho TC. Brain, Behavior, & Immunity – Health  Read it free ↗

Neighborhood Socioeconomic Disadvantage and White Matter Microstructure of the Arcuate Fasciculus and Uncinate Fasciculus in Adolescents FREE TO READ

Kulla A, Coury SM, Garcia JM, Teresi GI, Sisk LM, Hansen M, Miller JG, Gotlib IH, Ho TC. Biological Psychiatry Global Open Science  Read it free ↗

2023

Early life stress, sleep disturbances, and depressive symptoms during adolescence: The role of the cingulum bundle FREE TO READ

Uy JP, Ho TC, Buthmann JL, Coury SM, Gotlib IH. Developmental Cognitive Neuroscience  Read it free ↗

Effects of the Covid-19 Pandemic on Mental Health and Brain Maturation in Adolescents: Implications for Analyzing Longitudinal Data FREE TO READ

Gotlib IH, Miller JG, Borchers LR, Coury SM, Costella LA, Garcia JM, Ho TC. Biological Psychiatry Global Open Science  Read it free ↗

Early life stress moderates the relation between systemic inflammation and neural activation to reward in adolescents both cross-sectionally and longitudinally FREE TO READ

Yuan JP, Coury SM, Ho TC, Gotlib IH. Neuropsychopharmacology  Read it free ↗

Preparation and processing of dried blood spots for microRNA sequencing FREE TO READ

Morgunova A, Ibrahim P, Chen GG, Coury SM, Turecki G, Meaney MJ, Gifuni A, Gotlib IH, Nagy C, Ho TC. Biology Methods and Protocols  Read it free ↗

How Obstructed Action Efficacy Impacts Reward-based Decision-making in Adolescent Depression: An fMRI Study FREE TO READ

Harlé KM, Ho TC, Connolly CG, Simmons AN, Yang TT. Journal of the American Academy of Child & Adolescent Psychiatry  Read it free ↗

Integrating Biobehavioral and Environmental Components of Developmental Psychopathology via Interpersonal Dynamics: An RDoC-Advancing Model FREE TO READ

Somers JA, Ho TC, Roubinov D, Lee SS. Research on Child and Adolescent Psychopathology  Read it free ↗

The effects of puberty and sex on adolescent white matter development: A systematic review FREE TO READ

Pierkarski DJ, Colich NL, Ho TC. Developmental Cognitive Neuroscience  Read it free ↗

Editorial: How Racial and Ethnic Discrimination Gets Under the Skin: Inflammatory Outcomes in Adolescents and Young Adults of Color FREE TO READ

Ho TC. Biological Psychiatry: Global Open Science  Read it free ↗

2022

Early life stress, systemic inflammation, and neural correlates of implicit emotion regulation in adolescents FREE TO READ

Yuan JP, Ho TC, Coury SM, Chahal R, Colich NL, Gotlib IH. Brain, Behavior, and Immunity  Read it free ↗

Social threat, fronto-cingulate-limbic morphometry, and symptom course in depressed adolescents: a longitudinal investigation FREE TO READ

Ojha A, Teresi GI, Slavich GM, Gotlib IH, Ho TC. Psychological Medicine  Read it free ↗

Longitudinal change in adolescent depression and anxiety symptoms from before to during the COVID-19 pandemic FREE TO READ

Barendse MEA, Flannery J, Cavanagh C, Aristizabal M, Becker SP, Berger E, Breaux R, Campione-Barr N, Church JA, Crone EA, Dahl RE, Dennis-Tiwary TA, Dvorsky MR, Dziura SL, van de Groep S, Ho TC, Killoren SE, Langberg JM, Larguinho TL, Magis-Weinberg L, Michalska KJ, Mullins JL, Nadel H, Porter BM, Prinstein MJ, Redcay E, Rose AJ, Rote WM, Roy AK, Sweijen SW, Telzer EH, Teresi GI, Thomas GT, Pfeifer JH. Journal of Research on Adolescence  Read it free ↗

Heart rate variability moderates the effects of COVID-19-related stress and family adversity on emotional problems in adolescents: Testing models of differential susceptibility and diathesis stress FREE TO READ

Miller JG, Chahal R, Kirshenbaum JS, Ho TC, Gotlib IH. Development and Psychopathology  Read it free ↗

Editorial: Predicting Depression Risk in Adolescents from Multimodal Data: Current Evidence and Future Directions

Ho TC. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Multi-level predictors of depression symptoms in the Adolescent Brain Cognitive Development (ABCD) study FREE TO READ

Ho TC, Shah R, Mishra J, May AC, Tapert SF. Journal of Child Psychology and Psychiatry  Read it free ↗

Inflammatory cytokines and callosal white matter microstructure in adolescents FREE TO READ

Ho TC, Kulla A, Teresi GI, Sisk LM, Rosenberg-Hasson Y, Maecker HT, Gotlib IH. Brain, Behavior, and Immunity  Read it free ↗

Sex-specific vulnerability to depressive symptoms across adolescence and during the COVID-19 pandemic: The role of the cingulum bundle FREE TO READ

Chahal R, Ho TC, Miller JG, Borchers LR, Gotlib IH. JCPP Advances  Read it free ↗

2021

The effect of obstructed action efficacy on reward-based decision-making in healthy adolescents: a novel functional MRI task to assay frustration FREE TO READ

Harlé KM, Ho TC, Connolly CG, Simmons AN, Yang TT. Cognitive, Affective, & Behavioral Neuroscience  Read it free ↗

Testing a Developmental Model of Positive Parenting, Amygdala–Subgenual Anterior Cingulate Cortex Connectivity, and Depressive Symptoms in Adolescents Before and During the COVID-19 Pandemic FREE TO READ

Miller JG, Ho TC, Kirshenbaum JS, Chahal R, Gifuni AJ, Gotlib IH. Biological Psychiatry Global Open Science  Read it free ↗

Mechanisms of neuroplasticity linking early adversity to depression: developmental considerations FREE TO READ

Ho TC, King LS. Translational Psychiatry  Read it free ↗

Correlates and predictors of the severity of suicidal ideation in adolescence: an examination of brain connectomics and psychosocial characteristics FREE TO READ

Kirshenbaum JS, Chahal R, Ho TC, King LS, Gifuni AJ, Mastrovito D, Coury SM, Weisenburger RL, Gotlib IH. The Journal of Child Psychology and Psychiatry  Read it free ↗

Sex differences in myelin content of white matter tracts in adolescents with depression FREE TO READ

Ho TC, Sisk LM, Kulla A, Teresi GI, Hansen MM, Wu H, Gotlib IH. Neuropsychopharmacology  Read it free ↗

Editorial: Toward Neurobiological-Based Treatments of Depression and Anxiety: A Potential Case for the Nucleus Accumbens.

Ho TC. Journal of the American Academy of Child and Adolescent Psychiatry

Psychobiological risk factors for suicidal thoughts and behaviors in adolescence: a consideration of the role of puberty FREE TO READ

Ho TC, Gifuni AJ, Gotlib IH. Molecular Psychiatry  Read it free ↗

Brain cortical and subcortical morphology in adolescents with depression and a history of suicide attempt. FREE TO READ

Gifuni AJ, Chakravarty MM, Lepage M, Ho TC, Geoffroy MC, Lacourse E, Gotlib IH, Turecki G, Renaud J, Jollant F. Journal of Psychiatry & Neuroscience  Read it free ↗

Higher Levels of Pro-inflammatory Cytokines Are Associated With Higher Levels of Glutamate in the Anterior Cingulate Cortex in Depressed Adolescents FREE TO READ

Ho TC, Teresi GI, Segarra JR, Ojha A, Walker JC, Gu M, Spielman DM, Sacchet MD, Jiang F, Rosenberg-Hasson Y, Maecker H, Gotlib IH. Frontiers in Psychiatry  Read it free ↗

Sex differences in pubertal associations with fronto-accumbal white matter morphometry: Implications for understanding sensitivity to reward and punishment FREE TO READ

Chahal R, Delevich K, Kirshenbaum JS, Borchers LR, Ho TC, Gotlib IH. NeuroImage  Read it free ↗

Greater age-related changes in white matter morphometry following early life stress: Associations with internalizing problems in adolescence FREE TO READ

Chahal R, Kirshenbaum JS, Ho TC, Mastrovito D, Gotlib IH. Developmental Cognitive Neuroscience  Read it free ↗

White-matter tract connecting anterior insula to nucleus accumbens predicts greater future motivation in adolescents FREE TO READ

Leong JK, Ho TC, Colich NL, Sisk L, Knutson B, Gotlib IH. Developmental Cognitive Neuroscience  Read it free ↗

Smaller caudate gray matter volume is associated with greater implicit suicidal ideation in depressed adolescents FREE TO READ

Ho TC, Teresi GI, Ojha A, Walker JC, Kirshenbaum JS, Singh MK, Gotlib IH. Journal of Affective Disorders  Read it free ↗

Default mode and salience network alterations in suicidal and non-suicidal self-injurious thoughts and behaviors in adolescents with depression FREE TO READ

Ho TC, Walker JC, Teresi GI, Kulla A, Kirshenbaum JS, Gifuni AJ, Singh MK, Gotlib IH. Translational Psychiatry  Read it free ↗

2020

Study Protocol for Teen Inflammation Glutamate Emotion Research (TIGER) FREE TO READ

Walker JC, Teresi GI, Weisenburger RL, Segarra JR, Ojha A, Kulla A, Sisk L, Gu M, Spielman DM, Rosenberg-Hasson Y, Maecker HT, Gotlib IH, Ho TC. Frontiers in Human Neuroscience  Read it free ↗

Early Life Stress, Frontoamygdala Connectivity, and Biological Aging in Adolescence: A Longitudinal Investigation. FREE TO READ

Miller JG, Ho TC, Humphreys KL, King LS, Foland-Ross LC, Colich NL, Ordaz SJ, Lin J, Gotlib IH. Cerebral Cortex  Read it free ↗

Sex differences in the effects of gonadal hormones on white matter microstructure development in adolescence. FREE TO READ

Ho TC, Colich NL, Sisk LM, Oskirko K, Jo B, Gotlib IH. Developmental Cognitive Neuroscience  Read it free ↗

Higher Executive Control Network Coherence Buffers Against Puberty-Related Increases in Internalizing Symptoms During the COVID-19 Pandemic FREE TO READ

Chahal R, Kirshenbaum JS, Miller JG, Ho TC, Gotlib IH. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging  Read it free ↗

2019

Stress and Neurodevelopment in Adolescent Depression. FREE TO READ

Ho TC. Biological Psychiatry  Read it free ↗

Early life stress, cortisol, frontolimbic connectivity, and depressive symptoms during puberty. FREE TO READ

Kircanski K, Sisk LM, Ho TC, Humphreys KL, King LS, Colich NL, Ordaz SJ, Gotlib IH. Developmental Psychopathology  Read it free ↗

Anxiety and Attentional Bias in Children with Specific Learning Disorders.

Haft SL, Duong PH, Ho TC, Hendren RL, Hoeft F. Journal of Abnormal Child Psychology

Resting-state functional connectivity and inflexibility of daily emotions in major depression.

Schwartz J, Ordaz SJ, Kircanski K, Ho TC, Davis EG, Camacho MC, Gotlib IH. Journal of Affective Disorders

Test-Retest Reliability of Graph Theoretic Metrics in Adolescent Brains.

Yuan JP, Henje Blom E, Flynn T, Chen Y, Ho TC, Connolly CG, Dumont Walter RA, Yang TT, Xu D, Tymofiyeva O. Brain Connectivity

Evidence for a sensitive period in the effects of early life stress on hippocampal volume. FREE TO READ

Humphreys KL, King LS, Sacchet MD, Camacho MC, Colich NL, Ordaz SJ, Ho TC, Gotlib IH. Developmental Science  Read it free ↗

Reward-circuit biomarkers of risk and resilience in adolescent depression.

Fischer AS, Ellwood-Lowe ME, Colich NL, Cichocki A, Ho TC, Gotlib IH. Journal of Affective Disorders

Longitudinal decreases in suicidal ideation are associated with increases in salience network coherence in depressed adolescents.

Schwartz J, Ordaz SJ, Ho TC, Gotlib IH. Journal of Affective Disorders

2018

Reduced dorsal striatal gray matter volume predicts implicit suicidal ideation in adolescents. FREE TO READ

Ho TC, Cichocki AC, Gifuni AJ, Catalina Camacho M, Ordaz SJ, Singh MK, Gotlib IH. Read it free ↗

An exploratory examination of reappraisal success in depressed adolescents: Preliminary evidence of functional differences in cognitive control brain regions

LeWinn KZ, Strigo IA, Connolly CG, Ho TC, Tymofiyeva O, Sacchet MD, Weng HY, Blom EH, Simmons AN, Yang TT. Journal of Affective Disorders

Network-based approaches to examining stress in the adolescent brain. FREE TO READ

Ho TC, Dennis EL, Thompson PM, Gotlib IH. Neurobiology of Stress  Read it free ↗

Neural Markers of Resilience in Adolescent Females at Familial Risk for Major Depressive Disorder. FREE TO READ

Fischer AS, Camacho MC, Ho TC, Whitfield-Gabrieli S, Gotlib IH. JAMA Psychiatry  Read it free ↗

High levels of mitochondrial DNA are associated with adolescent brain structural hypoconnectivity and increased anxiety but not depression.

Tymofiyeva O, Henje Blom E, Ho TC, Connolly CG, Lindqvist D, Wolkowitz OM, Lin J, LeWinn KZ, Sacchet MD, Han LKM, Yuan JP, Bhandari SP, Xu D, Yang TT. Journal of Affective Disorders

Preferences for Depression Help-Seeking Among Vietnamese American Adults. FREE TO READ

Kim-Mozeleski JE, Tsoh JY, Gildengorin G, Cao LH, Ho T, Kohli S, Lam H, Wong C, Stewart S, McPhee SJ, Nguyen TT. Community Mental Health Journal  Read it free ↗

Network basis of suicidal ideation in depressed adolescents FREE TO READ

Ordaz SJ, Goyer MS, Ho TC, Singh MK, Gotlib IH. Journal of Affective Disorders  Read it free ↗

2017

The association between early life stress and prefrontal cortex activation during implicit emotion regulation is moderated by sex in early adolescence. FREE TO READ

Colich NL, Williams ES, Ho TC, King LS, Humphreys KL, Price AN, Ordaz SJ, Gotlib IH. Development and Psychopathology  Read it free ↗

Toward an Improved Understanding of Corticobasal Ganglia Reward Circuitry in Adolescent Depression.

Ho TC, Auerbach RP. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Effects of sensitivity to life stress on uncinate fasciculus segments in early adolescence. FREE TO READ

Ho TC, King LS, Leong JK, Colich NL, Humphreys KL, Ordaz SJ, Gotlib IH. Social Cognitive and Affective Neuroscience  Read it free ↗

Like mother like daughter: putamen activation as a mechanism underlying intergenerational risk for depression. FREE TO READ

Colich NL, Ho TC, Ellwood-Lowe ME, Foland-Ross LC, Sacchet MD, LeMoult JL, Gotlib IH. Social Cognitive and Affective Neuroscience  Read it free ↗

Hyperactivation in Cognitive Control and Visual Attention Brain Regions During Emotional Interference in Adolescent Depression.

Colich NL, Ho TC, Foland-Ross LC, Eggleston C, Ordaz SJ, Singh MK, Gotlib IH. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging

Inflexible Functional Connectivity of the Dorsal Anterior Cingulate Cortex in Adolescent Major Depressive Disorder. FREE TO READ

Ho TC, Sacchet MD, Connolly CG, Margulies DS, Tymofiyeva O, Paulus MP, Simmons AN, Gotlib IH, Yang TT. Neuropsychopharmacology  Read it free ↗

Resting-state functional connectivity of the amygdala and longitudinal changes in depression severity in adolescent depression. FREE TO READ

Connolly CG, Ho TC, Blom EH, LeWinn KZ, Sacchet MD, Tymofiyeva O, Simmons AN, Yang TT. Journal of Affective Disorders  Read it free ↗

DTI-based connectome analysis of adolescents with major depressive disorder reveals hypoconnectivity of the right caudate. FREE TO READ

Tymofiyeva O, Connolly CG, Ho TC, Sacchet MD, Henje Blom E, LeWinn KZ, Xu D, Yang TT. Journal of Affective Disorders  Read it free ↗

2016

Feasibility and Preliminary Efficacy of a Novel RDoC-Based Treatment Program for Adolescent Depression: “Training for Awareness Resilience and Action” (TARA)-A Pilot Study. FREE TO READ

Henje Blom E, Tymofiyeva O, Chesney MA, Ho TC, Moran P, Connolly CG, Duncan LG, Baldini L, Weng HY, Acree M, Goldman V, Hecht FM, Yang TT. Frontiers in Psychiatry  Read it free ↗

Intergenerational Neuroimaging of Human Brain Circuitry. FREE TO READ

Ho TC, Sanders SJ, Gotlib IH, Hoeft F. Trends in Neuroscience  Read it free ↗

Large-Scale Hypoconnectivity Between Resting-State Functional Networks in Unmedicated Adolescent Major Depressive Disorder. FREE TO READ

Sacchet MD, Ho TC, Connolly CG, Tymofiyeva O, Lewinn KZ, Han LK, Blom EH, Tapert SF, Max JE, Frank GK, Paulus MP, Simmons AN, Gotlib IH, Yang TT. Neuropsychopharmacology  Read it free ↗

Fusiform Gyrus Dysfunction is Associated with Perceptual Processing Efficiency to Emotional Faces in Adolescent Depression: A Model-Based Approach. FREE TO READ

Ho TC, Zhang S, Sacchet MD, Weng H, Connolly CG, Henje Blom E, Han LK, Mobayed NO, Yang TT. Frontiers in Psychology  Read it free ↗

The neuroscience and context of adolescent depression. FREE TO READ

Henje Blom E, Ho TC, Connolly CG, LeWinn KZ, Sacchet MD, Tymofiyeva O, Weng HY, Yang TT. Acta Paediatrica  Read it free ↗

2015

Peripheral telomere length and hippocampal volume in adolescents with major depressive disorder. FREE TO READ

Henje Blom E, Han LK, Connolly CG, Ho TC, Lin J, LeWinn KZ, Simmons AN, Sacchet MD, Mobayed N, Luna ME, Paulus M, Epel ES, Blackburn EH, Wolkowitz OM, Yang TT. Translational Psychiatry  Read it free ↗

Altered insular activation and increased insular functional connectivity during sad and happy face processing in adolescent major depressive disorder.

Henje Blom E, Connolly CG, Ho TC, LeWinn KZ, Mobayed N, Han L, Paulus MP, Wu J, Simmons AN, Yang TT. Journal of Affective Disorders

Emotion-Dependent Functional Connectivity of the Default Mode Network in Adolescent Depression.

Ho TC, Connolly CG, Henje Blom E, LeWinn KZ, Strigo IA, Paulus MP, Frank G, Max JE, Wu J, Chan M, Tapert SF, Simmons AN, Yang TT. Biological Psychiatry

2014

The development of an RDoC-based treatment program for adolescent depression: “Training for Awareness, Resilience, and Action” (TARA). FREE TO READ

Henje Blom E, Duncan LG, Ho TC, Connolly CG, LeWinn KZ, Chesney M, Hecht FM, Yang TT. Frontiers in Human Neuroscience  Read it free ↗

White matter correlates of adolescent depression: structural evidence for frontolimbic disconnectivity. FREE TO READ

LeWinn KZ, Connolly CG, Wu J, Drahos M, Hoeft F, Ho TC, Simmons AN, Yang TT. Journal of the American Academy of Child & Adolescent Psychiatry  Read it free ↗

Variability in visual working memory ability limits the efficiency of perceptual decision making. FREE TO READ

Ester EF, Ho TC, Brown SD, Serences JT. Journal of Vision  Read it free ↗

Functional connectivity of negative emotional processing in adolescent depression. FREE TO READ

Ho TC, Yang G, Wu J, Cassey P, Brown SD, Hoang N, Chan M, Connolly CG, Henje-Blom E, Duncan LG, Chesney MA, Paulus MP, Max JE, Patel R, Simmons AN, Yang TT. Journal of Affective Disorders  Read it free ↗

2013

Resting-state functional connectivity of subgenual anterior cingulate cortex in depressed adolescents. FREE TO READ

Connolly CG, Wu J, Ho TC, Hoeft F, Wolkowitz O, Eisendrath S, Frank G, Hendren R, Max JE, Paulus MP, Tapert SF, Banerjee D, Simmons AN, Yang TT. Biological Psychiatry  Read it free ↗

Altered cerebral perfusion in executive, affective, and motor networks during adolescent depression. FREE TO READ

Ho TC, Wu J, Shin DD, Liu TT, Tapert SF, Yang G, Connolly CG, Frank GK, Max JE, Wolkowitz O, Eisendrath S, Hoeft F, Banerjee D, Hood K, Hendren RL, Paulus MP, Simmons AN, Yang TT. Journal of the American Academy of Child & Adolescent Psychiatry  Read it free ↗

2012

Target enhancement and distractor suppression in naturalistic visual search. FREE TO READ

Ho TC, Ester EF. The Journal of Neuroscience  Read it free ↗

Perceptual consequences of feature-based attentional enhancement and suppression. FREE TO READ

Ho TC, Brown S, Abuyo NA, Ku EH, Serences JT. Journal of Vision  Read it free ↗

Evidence TRPV4 contributes to mechanosensitive ion channels in mouse skeletal muscle fibers. FREE TO READ

Ho TC, Horn NA, Huynh T, Kelava L, Lansman JB. Channels  Read it free ↗

The optimality of sensory processing during the speed-accuracy tradeoff. FREE TO READ

Ho T, Brown S, van Maanen L, Forstmann BU, Wagenmakers EJ, Serences JT. The Journal of Neuroscience  Read it free ↗

Open Access / Free to Read

Freely available to read in full — no journal subscription needed

2025

Value-Based Cognitive Control Moderates the Relation of Inflammation with Depression in Adolescents

Yuan JP, Miller JG, Joachimsthaler J, Uy JP, Ho TC, Gotlib IH. Social Cognitive and Affective Neuroscience  Read it free ↗

Interleukin-6 and Tumor Necrosis Factor-Alpha as Predictive Biomarkers for Depression and Mania in Young Adults with Mood Disorders

S Liu, G Morgan-Fleming, DM Denenny, SJ Frey, MR Irwin, DJ Miklowitz, Ho TC. Journal of Psychiatric Research  Read it free ↗

Connectome-based predictive models optimized for sleep differentiate patients with depression from psychiatrically healthy controls

Mummaneni A, Amir C, Allen NB, Ho TC. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging  Read it free ↗

Inflexible functional connectivity from rest to acute stress in alcohol use disorder

Kirsch DE, Ho TC, Wassum KM, Ray LA, Grodin EN. Addiction Biology  Read it free ↗

The effects of the COVID-19 pandemic on neurobiological functioning in adolescents

Yuan JP, Borchers LB, Lee Y, Buthmann J, Coury SM, Joachimsthaler J, Jaeger E, Ho TC, Gotlib IH. Translational Psychiatry  Read it free ↗

Peripheral microRNA signatures in adolescent depression

Morgunova A, O’Toole N, Abboud F, Coury SM, Chen GG, Teixeira M, Turecki G, Silveira PP, Gifuni AJ, Gotlib IH, Nagy C, Meaney MJ, Ho TC, Flores C. Biological Psychiatry: Global Open Science  Read it free ↗

2024

A mega-analysis of functional connectivity and network abnormalities in youth depression

Tse NY, Ratheesh A, Tian YE, Connolly CG, Davey CG, Ganesan S, Gotlib IH, Harrison BJ, Han LKM, Ho TC, Jamieson AJ, Kirshenbaum JS, Liu Y, Ma X, Ojha A, Qiu J, Sacchet MD, Schmaal L, Simmons AN, Suckling J, Wei D, Yang X, Yang TT, Cash RFH, Zalesky A. Nature Mental Health  Read it free ↗

Socioeconomic disadvantage moderates the association of systemic inflammation with amygdala volume in adolescents over a 2-year interval: an exploratory study

Yuan JP, Jaeger EL, Coury SM, Uy JP, Buthmann JL, Ho TC, Gotlib IH. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging  Read it free ↗

Neural correlates of depression-related smartphone language use in adolescents

McNeilly EA, Teresi GI, Coury SM, Bajwa Z, Kahn LE, Crowley R, Allen NB, Ho TC. NPP – Digital Psychiatry and Neuroscience  Read it free ↗

Threat- and reward-related brain circuitry, perceived stress, and anxiety in adolescents during the COVID-19 pandemic: a longitudinal investigation

Borchers LR, Gifuni AJ, Ho TC, Kirshenbaum JS, Gotlib IH. Social Cognitive and Affective Neuroscience  Read it free ↗

Examining putamen resting-state connectivity markers of suicide attempt history in depressed adolescents

Tymofiyeva O, Ho TC, Connolly CG, Gorrell S, Rampersaud R, Darrow SM, Max JE, Yang TT. Frontiers in Psychiatry  Read it free ↗

Neighborhood disadvantage and parenting predict longitudinal clustering of uncinate fasciculus microstructural integrity and clinical symptomatology in adolescents

Buthmann JL, Uy JP, Yuan JP, Coury SM, Ho TC, Gotlib IH. Developmental Cognitive Neuroscience  Read it free ↗

Exploring sex differences in trajectories of pubertal development and mental health following early adversity

Ho TC, Buthmann JL, Chahal R, Miller JG, Gotlib IH. Psychoneuroendocrinology  Read it free ↗

Protocol for teen inflammation glutamate emotion research (TIGER): Toward predictors of treatment response and clinical course in depressed adolescents

Coury SM, López V, Bajwa Z, Garcia JM, Teresi GI, Kuhlman KR, Li Y, Cole S, Miklowitz DJ, Pappas I, Ho TC. Brain, Behavior, & Immunity – Health  Read it free ↗

Neighborhood Socioeconomic Disadvantage and White Matter Microstructure of the Arcuate Fasciculus and Uncinate Fasciculus in Adolescents

Kulla A, Coury SM, Garcia JM, Teresi GI, Sisk LM, Hansen M, Miller JG, Gotlib IH, Ho TC. Biological Psychiatry Global Open Science  Read it free ↗

2023

Early life stress, sleep disturbances, and depressive symptoms during adolescence: The role of the cingulum bundle

Uy JP, Ho TC, Buthmann JL, Coury SM, Gotlib IH. Developmental Cognitive Neuroscience  Read it free ↗

Effects of the Covid-19 Pandemic on Mental Health and Brain Maturation in Adolescents: Implications for Analyzing Longitudinal Data

Gotlib IH, Miller JG, Borchers LR, Coury SM, Costella LA, Garcia JM, Ho TC. Biological Psychiatry Global Open Science  Read it free ↗

Early life stress moderates the relation between systemic inflammation and neural activation to reward in adolescents both cross-sectionally and longitudinally

Yuan JP, Coury SM, Ho TC, Gotlib IH. Neuropsychopharmacology  Read it free ↗

Preparation and processing of dried blood spots for microRNA sequencing

Morgunova A, Ibrahim P, Chen GG, Coury SM, Turecki G, Meaney MJ, Gifuni A, Gotlib IH, Nagy C, Ho TC. Biology Methods and Protocols  Read it free ↗

How Obstructed Action Efficacy Impacts Reward-based Decision-making in Adolescent Depression: An fMRI Study

Harlé KM, Ho TC, Connolly CG, Simmons AN, Yang TT. Journal of the American Academy of Child & Adolescent Psychiatry  Read it free ↗

Integrating Biobehavioral and Environmental Components of Developmental Psychopathology via Interpersonal Dynamics: An RDoC-Advancing Model

Somers JA, Ho TC, Roubinov D, Lee SS. Research on Child and Adolescent Psychopathology  Read it free ↗

The effects of puberty and sex on adolescent white matter development: A systematic review

Pierkarski DJ, Colich NL, Ho TC. Developmental Cognitive Neuroscience  Read it free ↗

Editorial: How Racial and Ethnic Discrimination Gets Under the Skin: Inflammatory Outcomes in Adolescents and Young Adults of Color

Ho TC. Biological Psychiatry: Global Open Science  Read it free ↗

2022

Early life stress, systemic inflammation, and neural correlates of implicit emotion regulation in adolescents

Yuan JP, Ho TC, Coury SM, Chahal R, Colich NL, Gotlib IH. Brain, Behavior, and Immunity  Read it free ↗

Social threat, fronto-cingulate-limbic morphometry, and symptom course in depressed adolescents: a longitudinal investigation

Ojha A, Teresi GI, Slavich GM, Gotlib IH, Ho TC. Psychological Medicine  Read it free ↗

Longitudinal change in adolescent depression and anxiety symptoms from before to during the COVID-19 pandemic

Barendse MEA, Flannery J, Cavanagh C, Aristizabal M, Becker SP, Berger E, Breaux R, Campione-Barr N, Church JA, Crone EA, Dahl RE, Dennis-Tiwary TA, Dvorsky MR, Dziura SL, van de Groep S, Ho TC, Killoren SE, Langberg JM, Larguinho TL, Magis-Weinberg L, Michalska KJ, Mullins JL, Nadel H, Porter BM, Prinstein MJ, Redcay E, Rose AJ, Rote WM, Roy AK, Sweijen SW, Telzer EH, Teresi GI, Thomas GT, Pfeifer JH. Journal of Research on Adolescence  Read it free ↗

Heart rate variability moderates the effects of COVID-19-related stress and family adversity on emotional problems in adolescents: Testing models of differential susceptibility and diathesis stress

Miller JG, Chahal R, Kirshenbaum JS, Ho TC, Gotlib IH. Development and Psychopathology  Read it free ↗

Multi-level predictors of depression symptoms in the Adolescent Brain Cognitive Development (ABCD) study

Ho TC, Shah R, Mishra J, May AC, Tapert SF. Journal of Child Psychology and Psychiatry  Read it free ↗

Inflammatory cytokines and callosal white matter microstructure in adolescents

Ho TC, Kulla A, Teresi GI, Sisk LM, Rosenberg-Hasson Y, Maecker HT, Gotlib IH. Brain, Behavior, and Immunity  Read it free ↗

Sex-specific vulnerability to depressive symptoms across adolescence and during the COVID-19 pandemic: The role of the cingulum bundle

Chahal R, Ho TC, Miller JG, Borchers LR, Gotlib IH. JCPP Advances  Read it free ↗

2021

The effect of obstructed action efficacy on reward-based decision-making in healthy adolescents: a novel functional MRI task to assay frustration

Harlé KM, Ho TC, Connolly CG, Simmons AN, Yang TT. Cognitive, Affective, & Behavioral Neuroscience  Read it free ↗

Testing a Developmental Model of Positive Parenting, Amygdala–Subgenual Anterior Cingulate Cortex Connectivity, and Depressive Symptoms in Adolescents Before and During the COVID-19 Pandemic

Miller JG, Ho TC, Kirshenbaum JS, Chahal R, Gifuni AJ, Gotlib IH. Biological Psychiatry Global Open Science  Read it free ↗

Mechanisms of neuroplasticity linking early adversity to depression: developmental considerations

Ho TC, King LS. Translational Psychiatry  Read it free ↗

Correlates and predictors of the severity of suicidal ideation in adolescence: an examination of brain connectomics and psychosocial characteristics

Kirshenbaum JS, Chahal R, Ho TC, King LS, Gifuni AJ, Mastrovito D, Coury SM, Weisenburger RL, Gotlib IH. The Journal of Child Psychology and Psychiatry  Read it free ↗

Sex differences in myelin content of white matter tracts in adolescents with depression

Ho TC, Sisk LM, Kulla A, Teresi GI, Hansen MM, Wu H, Gotlib IH. Neuropsychopharmacology  Read it free ↗

Psychobiological risk factors for suicidal thoughts and behaviors in adolescence: a consideration of the role of puberty

Ho TC, Gifuni AJ, Gotlib IH. Molecular Psychiatry  Read it free ↗

Brain cortical and subcortical morphology in adolescents with depression and a history of suicide attempt.

Gifuni AJ, Chakravarty MM, Lepage M, Ho TC, Geoffroy MC, Lacourse E, Gotlib IH, Turecki G, Renaud J, Jollant F. Journal of Psychiatry & Neuroscience  Read it free ↗

Higher Levels of Pro-inflammatory Cytokines Are Associated With Higher Levels of Glutamate in the Anterior Cingulate Cortex in Depressed Adolescents

Ho TC, Teresi GI, Segarra JR, Ojha A, Walker JC, Gu M, Spielman DM, Sacchet MD, Jiang F, Rosenberg-Hasson Y, Maecker H, Gotlib IH. Frontiers in Psychiatry  Read it free ↗

Sex differences in pubertal associations with fronto-accumbal white matter morphometry: Implications for understanding sensitivity to reward and punishment

Chahal R, Delevich K, Kirshenbaum JS, Borchers LR, Ho TC, Gotlib IH. NeuroImage  Read it free ↗

Greater age-related changes in white matter morphometry following early life stress: Associations with internalizing problems in adolescence

Chahal R, Kirshenbaum JS, Ho TC, Mastrovito D, Gotlib IH. Developmental Cognitive Neuroscience  Read it free ↗

White-matter tract connecting anterior insula to nucleus accumbens predicts greater future motivation in adolescents

Leong JK, Ho TC, Colich NL, Sisk L, Knutson B, Gotlib IH. Developmental Cognitive Neuroscience  Read it free ↗

Smaller caudate gray matter volume is associated with greater implicit suicidal ideation in depressed adolescents

Ho TC, Teresi GI, Ojha A, Walker JC, Kirshenbaum JS, Singh MK, Gotlib IH. Journal of Affective Disorders  Read it free ↗

Default mode and salience network alterations in suicidal and non-suicidal self-injurious thoughts and behaviors in adolescents with depression

Ho TC, Walker JC, Teresi GI, Kulla A, Kirshenbaum JS, Gifuni AJ, Singh MK, Gotlib IH. Translational Psychiatry  Read it free ↗

2020

Study Protocol for Teen Inflammation Glutamate Emotion Research (TIGER)

Walker JC, Teresi GI, Weisenburger RL, Segarra JR, Ojha A, Kulla A, Sisk L, Gu M, Spielman DM, Rosenberg-Hasson Y, Maecker HT, Gotlib IH, Ho TC. Frontiers in Human Neuroscience  Read it free ↗

Early Life Stress, Frontoamygdala Connectivity, and Biological Aging in Adolescence: A Longitudinal Investigation.

Miller JG, Ho TC, Humphreys KL, King LS, Foland-Ross LC, Colich NL, Ordaz SJ, Lin J, Gotlib IH. Cerebral Cortex  Read it free ↗

Sex differences in the effects of gonadal hormones on white matter microstructure development in adolescence.

Ho TC, Colich NL, Sisk LM, Oskirko K, Jo B, Gotlib IH. Developmental Cognitive Neuroscience  Read it free ↗

Higher Executive Control Network Coherence Buffers Against Puberty-Related Increases in Internalizing Symptoms During the COVID-19 Pandemic

Chahal R, Kirshenbaum JS, Miller JG, Ho TC, Gotlib IH. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging  Read it free ↗

2019

Stress and Neurodevelopment in Adolescent Depression.

Ho TC. Biological Psychiatry  Read it free ↗

Early life stress, cortisol, frontolimbic connectivity, and depressive symptoms during puberty.

Kircanski K, Sisk LM, Ho TC, Humphreys KL, King LS, Colich NL, Ordaz SJ, Gotlib IH. Developmental Psychopathology  Read it free ↗

Evidence for a sensitive period in the effects of early life stress on hippocampal volume.

Humphreys KL, King LS, Sacchet MD, Camacho MC, Colich NL, Ordaz SJ, Ho TC, Gotlib IH. Developmental Science  Read it free ↗

2018

Reduced dorsal striatal gray matter volume predicts implicit suicidal ideation in adolescents.

Ho TC, Cichocki AC, Gifuni AJ, Catalina Camacho M, Ordaz SJ, Singh MK, Gotlib IH. Social Cognitive and Affective Neuroscience  Read it free ↗

Network-based approaches to examining stress in the adolescent brain.

Ho TC, Dennis EL, Thompson PM, Gotlib IH. Neurobiology of Stress  Read it free ↗

Neural Markers of Resilience in Adolescent Females at Familial Risk for Major Depressive Disorder.

Fischer AS, Camacho MC, Ho TC, Whitfield-Gabrieli S, Gotlib IH. JAMA Psychiatry  Read it free ↗

Preferences for Depression Help-Seeking Among Vietnamese American Adults.

Kim-Mozeleski JE, Tsoh JY, Gildengorin G, Cao LH, Ho T, Kohli S, Lam H, Wong C, Stewart S, McPhee SJ, Nguyen TT. Community Mental Health Journal  Read it free ↗

Network basis of suicidal ideation in depressed adolescents

Ordaz SJ, Goyer MS, Ho TC, Singh MK, Gotlib IH. Journal of Affective Disorders  Read it free ↗

2017

The association between early life stress and prefrontal cortex activation during implicit emotion regulation is moderated by sex in early adolescence.

Colich NL, Williams ES, Ho TC, King LS, Humphreys KL, Price AN, Ordaz SJ, Gotlib IH. Development and Psychopathology  Read it free ↗

Effects of sensitivity to life stress on uncinate fasciculus segments in early adolescence.

Ho TC, King LS, Leong JK, Colich NL, Humphreys KL, Ordaz SJ, Gotlib IH. Social Cognitive and Affective Neuroscience  Read it free ↗

Like mother like daughter: putamen activation as a mechanism underlying intergenerational risk for depression.

Colich NL, Ho TC, Ellwood-Lowe ME, Foland-Ross LC, Sacchet MD, LeMoult JL, Gotlib IH. Social Cognitive and Affective Neuroscience  Read it free ↗

Inflexible Functional Connectivity of the Dorsal Anterior Cingulate Cortex in Adolescent Major Depressive Disorder.

Ho TC, Sacchet MD, Connolly CG, Margulies DS, Tymofiyeva O, Paulus MP, Simmons AN, Gotlib IH, Yang TT. Neuropsychopharmacology  Read it free ↗

Resting-state functional connectivity of the amygdala and longitudinal changes in depression severity in adolescent depression.

Connolly CG, Ho TC, Blom EH, LeWinn KZ, Sacchet MD, Tymofiyeva O, Simmons AN, Yang TT. Journal of Affective Disorders  Read it free ↗

DTI-based connectome analysis of adolescents with major depressive disorder reveals hypoconnectivity of the right caudate.

Tymofiyeva O, Connolly CG, Ho TC, Sacchet MD, Henje Blom E, LeWinn KZ, Xu D, Yang TT. Journal of Affective Disorders  Read it free ↗

2016

Feasibility and Preliminary Efficacy of a Novel RDoC-Based Treatment Program for Adolescent Depression: “Training for Awareness Resilience and Action” (TARA)-A Pilot Study.

Henje Blom E, Tymofiyeva O, Chesney MA, Ho TC, Moran P, Connolly CG, Duncan LG, Baldini L, Weng HY, Acree M, Goldman V, Hecht FM, Yang TT. Frontiers in Psychiatry  Read it free ↗

Intergenerational Neuroimaging of Human Brain Circuitry.

Ho TC, Sanders SJ, Gotlib IH, Hoeft F. Trends in Neuroscience  Read it free ↗

Large-Scale Hypoconnectivity Between Resting-State Functional Networks in Unmedicated Adolescent Major Depressive Disorder.

Sacchet MD, Ho TC, Connolly CG, Tymofiyeva O, Lewinn KZ, Han LK, Blom EH, Tapert SF, Max JE, Frank GK, Paulus MP, Simmons AN, Gotlib IH, Yang TT. Neuropsychopharmacology  Read it free ↗

Fusiform Gyrus Dysfunction is Associated with Perceptual Processing Efficiency to Emotional Faces in Adolescent Depression: A Model-Based Approach.

Ho TC, Zhang S, Sacchet MD, Weng H, Connolly CG, Henje Blom E, Han LK, Mobayed NO, Yang TT. Frontiers in Psychology  Read it free ↗

The neuroscience and context of adolescent depression.

Henje Blom E, Ho TC, Connolly CG, LeWinn KZ, Sacchet MD, Tymofiyeva O, Weng HY, Yang TT. Acta Paediatrica  Read it free ↗

2015

Peripheral telomere length and hippocampal volume in adolescents with major depressive disorder.

Henje Blom E, Han LK, Connolly CG, Ho TC, Lin J, LeWinn KZ, Simmons AN, Sacchet MD, Mobayed N, Luna ME, Paulus M, Epel ES, Blackburn EH, Wolkowitz OM, Yang TT. Translational Psychiatry  Read it free ↗

2014

The development of an RDoC-based treatment program for adolescent depression: “Training for Awareness, Resilience, and Action” (TARA).

Henje Blom E, Duncan LG, Ho TC, Connolly CG, LeWinn KZ, Chesney M, Hecht FM, Yang TT. Frontiers in Human Neuroscience  Read it free ↗

White matter correlates of adolescent depression: structural evidence for frontolimbic disconnectivity.

LeWinn KZ, Connolly CG, Wu J, Drahos M, Hoeft F, Ho TC, Simmons AN, Yang TT. Journal of the American Academy of Child & Adolescent Psychiatry  Read it free ↗

Variability in visual working memory ability limits the efficiency of perceptual decision making.

Ester EF, Ho TC, Brown SD, Serences JT. Journal of Vision  Read it free ↗

Functional connectivity of negative emotional processing in adolescent depression.

Ho TC, Yang G, Wu J, Cassey P, Brown SD, Hoang N, Chan M, Connolly CG, Henje-Blom E, Duncan LG, Chesney MA, Paulus MP, Max JE, Patel R, Simmons AN, Yang TT. Journal of Affective Disorders  Read it free ↗

2013

Resting-state functional connectivity of subgenual anterior cingulate cortex in depressed adolescents.

Connolly CG, Wu J, Ho TC, Hoeft F, Wolkowitz O, Eisendrath S, Frank G, Hendren R, Max JE, Paulus MP, Tapert SF, Banerjee D, Simmons AN, Yang TT. Biological Psychiatry  Read it free ↗

Altered cerebral perfusion in executive, affective, and motor networks during adolescent depression.

Ho TC, Wu J, Shin DD, Liu TT, Tapert SF, Yang G, Connolly CG, Frank GK, Max JE, Wolkowitz O, Eisendrath S, Hoeft F, Banerjee D, Hood K, Hendren RL, Paulus MP, Simmons AN, Yang TT. Journal of the American Academy of Child & Adolescent Psychiatry  Read it free ↗

2012

Target enhancement and distractor suppression in naturalistic visual search.

Ho TC, Ester EF. The Journal of Neuroscience  Read it free ↗

Perceptual consequences of feature-based attentional enhancement and suppression.

Ho TC, Brown S, Abuyo NA, Ku EH, Serences JT. Journal of Vision  Read it free ↗

Evidence TRPV4 contributes to mechanosensitive ion channels in mouse skeletal muscle fibers.

Ho TC, Horn NA, Huynh T, Kelava L, Lansman JB. Channels  Read it free ↗

The optimality of sensory processing during the speed-accuracy tradeoff.

Ho T, Brown S, van Maanen L, Forstmann BU, Wagenmakers EJ, Serences JT. The Journal of Neuroscience  Read it free ↗